AI Assistant Startups funded by Y Combinator (YC) 2025

Iris observes how you handle your day - how you reply, decide, prioritize - and prepares the next set of actions. Our key insight: if you model real behavior, you can replicate judgment, not just tasks using personal agents and knowledge graphs. Iris knows what needs your attention across your accounts, pre-fills the actions, and you can simply swipe right to hand it off to your agent. We started with connecting calendars and emails. We launched four weeks ago. Over 1,200 people have downloaded Iris, 168 use it every day, and they’ve taken more than 36,000 actions so far growing 48% week over week. In the future, everyone will have a personal proxy running their digital life with near perfect accuracy. Iris is the first real version of that future.

Jarmin.ai is your 24/7 ML eng employee that you hire. Just talk to Jarmin like any other employee and Jarmin handles your AI/ML work from there. Completely hand over full initiatives or individual tasks. Jarmin’s founding team is from Meta SuperIntelligence Labs (Staff Engineers), Apple (Machine Learning Engineer), AWS (scaling infra), Lockheed-Martin (Research), and JPMorganChase (SWE) with experience building AI/ML and automating complex work of Researchers, Data Scientists, ML Engineers with AI.

Saffron Health is building AI agents that automate specialist referrals for primary care. Primary care staff spend hours each day on tedious coordination work: searching for in-network specialists, filling out authorization forms, and chasing down medical records. Saffron's agents find available in-network providers, complete prior authorizations, and help patients book appointments, which lowers administrative costs and improves access to care.

item connects to all your customer tools, gathers and enriches context automatically, and becomes your company’s source of truth — one place where your team and your AI agents share the full picture to act autonomously. At the center is the Assistant — your sidekick for daily work. It can send follow-ups, research leads, or add deals with a simple prompt. No complex UI, drop-downs or fields, simply ask. For repeatable work, you build Agents that you can train like new hires, simply by writing documents that describe your processes. item Agents run business processes across sales, support, and account management autonomously.

We build AI that runs carrier operations. Lunavo is the AI assistant for carriers. It plugs directly into their existing toolstack, understands their processes, and monitors all incoming data and requests. Lunavo runs end-to-end backoffice operations, handling repetitive tasks, resolving issues autonomously, and escalating only what matters. Lunavo helps carriers scale operations without scaling headcount.

We've built an AI property manager that automates maintenance for real estate agents. Brickwise handles tenant calls and messages 24/7, following up by chasing contractors and resolving payments. This provides higher tenant satisfaction, while also simplifying the workloads of property managers. Our property manager operates across all communication channels, including SMS, WhatsApp, phone calls, and email, making it easy to integrate with existing workflows.

Logical is a desktop AI that acts as a proactive and largely promptless copilot, designed to reduce the friction of using AI for everyday tasks. It transfers context across apps, and allows taking action on many apps with just a few clicks. Logical can assist with drafting emails, writing docs, noting meetings and can even automatically detect action items. Need to prompt? Logical can understand intent in much fewer words than a regular chatbot. Plus, user data is never sent to Logical servers. Logical is the AI resurrection of Clippy, but actually good.

Sciloop is building an AI Co-Scientist that automates experimentation and analysis for machine learning researchers, allowing them to test ideas far faster than today’s tools allow. We are Bilal and Osman, International Physics Olympiad medalists and the only Pakistanis admitted to MIT in our respective years, with several years of hands-on ML research experience inside MIT CSAIL. We have built large-scale training pipelines, worked with terabyte-scale datasets, and seen the research bottleneck firsthand while contributing to scientific ML projects. We left MIT to solve this problem directly and are now building a system that can eventually accelerate scientific discovery itself. https://sciloop.dev

Aside listens to your sales calls and surfaces real-time answers pulled from your docs, HubSpot, or past calls. It's like pressing 𝚌𝚝𝚛𝚕+𝚟 on your company’s knowledge into every rep – so anyone can sound like your best rep. - 🔎 Shows answers from your docs, Slack, and past winning calls - 📝 Live coaching that catches what reps miss: Aside spots what reps skip during calls and guides every rep to apply your playbook - BANT, SPICED, or your own - not after, live. - 💬 Preload your cheatsheets as Live Cards: Turn your playbooks, FAQs, and notes into instant, in-call cards. - 🎓 Coaching feedback, remembered by AI: Aside reviews every call, gives feedback, and turns it into live suggestions for your next one - so you never repeat the same mistake.

Fastshot is a no-code mobile development platform. Our mission is to "Democratize mobile app creation with AI" Anyone can develop a mobile app from idea to App Stores within minutes just by chatting with AI.

Automate internal auditing (planning, testing, documenting) to comply better with financial regulations. Denki performs audit work with 99% software, 1% services: ✔️ Works on existing systems (e.g. Auditboard, Workiva, ERPs) ✔️ Automates Control processes (e.g. collects evidence, runs walkthrough interviews, tests) ✔️ Records every step for traceability (workpapers w/ full audit trace) Focused on SOX programs and financial regulations (SEC Rules etc.)

We automate customer communication with AI voice and chat assistants that answer, qualify, and follow up instantly. Internally, Bravi gives field and technical teams an AI copilot that can search hundreds of product documents and installation guides in seconds. Bravi is already used by leading installers and manufacturers across shutters, solar, windows and garage doors. One customer uncovered more than a thousand missed calls per month that Bravi now handles automatically, converting lost demand into new business. We’re becoming the AI layer for the multi-trillion-dollar home-services market.

Meet Meteor: a Chrome-alternative that can actually do your work for you. With agents getting better by the day (literally), we realize that it’s time to automate the boring, tedious work. We use your browser session to empower agents to act like your personal assistants (ex. book a calendar, find cheaper flights, buy clothes on amazon etc.) Some of Meteor’s features: - Chat with any page - Integrate with popular apps like Gmail, Google Calendar, Twitter etc. - Browser agent to autonomously navigate the web and perform tasks - More coming soon! We're excited to usher in a new era of browsing.

Pharmie is an AI assistant for pharmacies. It can pick up calls, process prescriptions, handle insurance follow-ups, and even help upsell specific drugs and services. Pharmacies can get 50+ phone calls a day, and missing phone calls means lost revenue from filling prescriptions. Pharmacy workflows are complex and custom to each pharmacy's needs. Generic tools are not enough, which is why AI agents can handle tasks end-to-end that previously could not be automated. We are constantly evolving Pharmie to become a suite of agents that supercharge your pharmacy. In the future, pharmacies will evolve into patient care centers, bridging the gaps in access caused by today’s overburdened healthcare system. Successful pharmacies will use AI to optimize their operations, resulting in a higher quality patient experience traditional pharmacies cannot match.

At Rid we're determined to make selling easier than buying. All you have to do is text us what you're selling, and we'll take care of the rest -- researching the product, listing on marketplaces, negotiating with buyers, answering questions, and handling delivery. We all have that thing we've been too lazy to sell. Rid makes it so easy we can't even be lazy.

Epicenter is an ecosystem of open-source, local-first apps. We store all your work—notes, transcripts, chat histories—in a single folder of plain text and SQLite. Every tool we build shares this memory: your text editor, personal assistant, etc.. It's open, tweakable, and yours. Grep it, open it in Obsidian, host it wherever you like. The choice is yours. Our vision is to build a personal workspace where you own your data, choose your own AI models, and replace siloed apps with open, interoperable alternatives. All while preserving authenticity and being free and open source. ❤️

Omnara is the command center for AI agents. We enable developers to launch AI agents like Claude Code on their laptop and then seamlessly continue working on mobile, freeing engineers from being desk-bound. With a growing community of users, Omnara is building the essential infrastructure for the era of AI agents.

April is a voice AI Executive assistant that manages your email and calendar, hands free. It’s built for busy individuals who need EAs but don’t have them.

SigmanticAI is building an AI-native hardware development assistant that automates the entire RTL design flow, from natural language to synthesizable HDL and testbenches, inside a seamless VSCode fork. Powered by fine-tuned Verilog LLMs, reinforcement learning, and real compiler feedback, SigmanticAI iteratively refines code until it compiles and passes synthesis, no matter how complex the design. It’s like the Cursor for HDL design. In addition to code generation, SigmanticAI can generate token-level annotations and onboarding documents to accelerate ramp-up for new engineers. With support for both cloud and on-prem deployment, it integrates with existing EDA tools to dramatically reduce debug time, improve collaboration, and accelerate hardware design across teams

Cleon is building an AI-native software implementation platform to speed up customer onboarding, beginning with a focus on ingesting complex Excel files with agentic AI. B2B SaaS companies have millions of dollars of contracted revenue sitting behind implementations. Cleon handles everything from the big picture (generating requirements and aligning stakeholders) to the details (data cleaning and schema mapping). The team consists of Alexandros (ex-athlete in rowing and engineer at a proptech startup), Rohan (engineer at a fintech startup with long implementations and at an SAP code migration startup), and Ric (banker at RBC and enterprise sales at Palantir).

Alkali is building the co-pilot for chemical process design. Spot design errors earlier, get the right equipment sooner, and build chemical projects faster.

Jeevy Fabrication is an AI-powered contractor that connects complex weld jobs to the best-fit shops—fast. We deliver top-tier QA and total transparency, all at better traditional outsourced pricing. Our software reduces bid and scheduling time for our in-network shops by over 80%. It converts manufacturing drawings into an accurate bill of materials and a resource-loaded, high-fidelity schedule—eliminating costly errors and rework. Using this our in-network fabricators can bid on more jobs and deliver more reliable results than their competitors. We also offer our clients a streamlined purchasing and project tracking experience. Clients submit purchase requests, track schedules, access key documents, and receive real-time photo updates—all in one place. We provide traceability for easy material review and maintenance of domestic content standards as required. Faster decisions, fewer delays, complete visibility.

Zero empowers knowledge workers by transforming the way they manage their email. It intelligently summarizes important messages, helps complete tasks, and even enables users to chat directly with their inbox.

Flott helps transport and logistics companies run leaner, smarter, and more profitable operations. Flott unifies everything transport and logistics teams need in a single, AI-powered control center—bringing planning, live tracking (gps, fuel, etc), invoicing, and payments into one place and delivering true end-to-end visibility. Flott’s AI agents act as an extension of fleet managers — automating repetitive tasks and optimizing workflows.This lets companies focus on what truly matters: growing the business.

Ovlo is a no-code AI platform for supply chain teams, building custom agents that automate critical workflows like demand forecasting, compliance validation, invoice reconciliation, and inventory optimization to eliminate manual errors and supercharge efficiency. As an AI layer connecting onto of your current tech stack, even email and Sheets, it creates streamlined end-to-end processes, empowering teams.

Truffle AI makes it easy for developers to integrate AI agents into any software application. We do this by exposing agents as simple APIs that can be called from anywhere. Developers have used Truffle to add customer support agents into WhatsApp and analytics agents into Slack.

Rebolt lets everyone in the company build apps, and agents by speaking with AI. Integrated with your company tools, data and authentication. Replacing no-code tools, bloated SaaS and complex spreadsheets, for automating all the boring work.

TamLabs transforms Microsoft Word into an AI-native document editor. Our plugin enables instant document changes with git-style previews, automated comment implementation, and formatting preservation.

Paratus Health is the AI operations layer for outpatient clinics. We build autonomous agents that don’t just assist staff - they replace them, fully handling front desk calls, patient intake, insurance verification, documentation, and billing prep. Everything is deeply integrated into EHRs like Epic and Athena, eliminating the need for fragmented tools and manual work. No toggling between systems. No busywork. Just one intelligent system running your clinical operations - faster, smarter, and more profitably than ever before.

G LNK is an AI-powered platform simplifying how healthcare companies connect with the relevant medical professionals. Our proprietary matching and ranking models instantly identify the most qualified experts, accelerating drug development and commercialization. Designed with compliance at its core, G LNK ensures every connection meets strict regulatory and ethical standards—empowering companies to innovate faster with confidence.

assistant-ui helps frontend developers add AI chat to their apps. Our product is used by several dozen companies, like LangChain, Stack AI, Browser Use, and Athena Intelligence. We're building an open source Typescript/React library and a backend as a service, with first class integrations into popular agent frameworks like LangGraph and Vercel AI SDK.

Caseflood.ai helps law firms cut costs by a third and increase average case value by 20% by replacing their entire admin/operations staff with AI agents. It takes care of all admin tasks - from client intake to case analysis to engaging clients - allowing for firms to be run more profitably and wildly more efficient. Caseflood.ai is on a mission to fundamentally change the unit economics of the legal industry.

Altrina automates SOPs to give humans back their time to do what matters. We have already significantly improved organizational efficiency for local governments, law offices, insurance brokers, consulting firms, and hedge funds. Formerly General Agency/Tessa AI

jo is a voice-first digital personality that works alongside you every day – a smart and efficient new friend who saves you time and money while improving your quality of life. As of now, jo runs only on macOS desktop, and only on Apple Silicon.

Edexia is an AI Teacher Assistant for grading essays. It can be trained and controlled by the teacher and can grade assignments from any curriculum, year level, subject, or format. Learning like a teacher, Edexia visually breaks down its understanding of the rubric, and updates this as a teacher corrects it. Our vision is to transform education by facilitating AI’s safe and effective integration across all institutions and applications. Not using AI to replace teachers but rather to empower them—providing them with all the time and resources they need to develop their students.

Vortexify AI is a platform for building fully operational AI workflows tailored to supply chain operations. Deploy specialized, task-specific AI bots in days — not weeks. Our platform streamlines the creation of AI bots that can analyze millions of data rows, manage complex, long-horizon processes, and collaborate seamlessly with humans in the loop. Each AI bot comes equipped with custom tools maintained through AI-powered code editors directly within the Vortexify platform. Development teams can instantly generate dashboards, data pipelines, machine learning models, and custom functions — all contextualized to business goals and data requirements. Bots can operate in Co-pilot or Agent (autonomous) mode. They can be scheduled or triggered by real-time alerts and are governed by robust, natural language-generated guardrail templates that ensure safety, compliance, and reliability.

Email sucks. It takes forever to go through, and hiring an assistant is costly and invasive. Friday is building the assistant that learns how to predict the action that you will take on your emails, and does it for you. Today's email products try to help you go through your emails a little faster, but if you have to get through 1000 emails, those products doesn't do much for you. The reality is, most of the emails you get don't require you to personally look at them. Friday completely eliminates the need to check those emails, and handles them all at once for you, immediately. Friday is here to file away spam, sift through newsletters for important tidbits, text you important notifications, and reply to mundane emails, so that no matter how many thousands of emails are in your inbox, you'll just be left with the few emails that actually require your personal touch. Getting this right is difficult, so everyone else settles with trying to help you go through your email twice as fast. If you want to go 100x as fast, you shouldn't spend even a second on useless emails. Friday gets this right, bringing the elite experience of having a professional assistant to the entire world.

Karmen is an AI assistant for construction project managers. We integrate with their emails, project management software and ERPs to automate admin tasks like invoice processing and approvals. One construction company we are working with faced a project delay cost of around $50,000 a day from an invoicing mistake. Supplier management issues like these account for 20% of project delays.

Capy is an AI software engineer that ships dozens of features in parallel. It works end-to-end - autonomously triaging issues, executing code in isolated VMs, and pushing PRs to GitHub.

Vespper is an AI document authoring platform for regulatory professionals in pharma, med-tech and biotech companies.

Sandra AI builds AI employees for car dealerships and auto repair shops, starting with AI receptionists. Dealerships miss 30% of customer calls, leading to 45% of customers switching dealerships and up to $2M in annual lost revenue per dealership. Sandra AI operates 24/7, handling calls, emails, and texts, and directly schedules appointments, ensuring no opportunity is lost.

We are building a fully local opensource software engineer. Software thrives on opensource tools and it's only right that this technology be built for all to use.

Consumers miss out on $70B+ every year because they're busy and unaware, and that money is sitting in their email inbox. So, we automated reading email receipts and claiming the money they're entitled to, offering a service to which you can sign up once, do (literally) nothing, and earn $. Where is this money coming from? - Retailers: When the price of clothes or furniture you've already bought drops, you're entitled to a refund for the difference - Airlines: When a flight you've booked gets delayed or canceled, you're entitled to a cash compensation. - Enterprises: When a class-action lawsuit is filed against a company you engage with, you're entitled to money. - And many more, that even the government holds some of your unclaimed funds. Today, the dream of one service that automatically claims the money you deserve when you shop, fly,... and live is (finally) possible. We started with automating refunds in the shopping industry and have secured $8,000 in refunds to our users, growing 233% MoM. With AI, we've been able to repurpose that same automation to tackle refunds in the flight industry and the class-action lawsuit landscape. Why us? (1) We're obsessed with reclaiming what's rightfully yours: Kamal and Anthony grew up in Lebanon, where people's money was unfairly taken away. (2) Weijie was the lead infra engineer for Wish's recommendation system, the feature that fueled their IPO. Our combined experience includes Apple, Addepar, Bolt, Wish, and StackAdapt. And we're all working towards one goal: move those billions of dollars where they belong.

Simple AI makes it easy to build and deploy enterprise-grade phone agents in days, not weeks. Iconic businesses use us for sales calls, customer support, leads qualification, and more.

Orca is an open source AI Agent for game development that enables everyone to make video games without learning coding, game engines, or art. We are integrating a chat bot, with complete access to Godot. The chatbot can: Read/edit/create/delete files Understand the entire project as context Create images and keep consistency across images created Create 2D characters and animations Edit Godot native objects, e.g. nodes, scenes, ...

Saldor is your voice-first email client that lets you triage, read, and respond to messages without touching your screen. Whether you’re commuting, cooking, or on the go, Saldor keeps you connected and productive entirely through natural conversation.

ProhostAI is building an AI Property Manager for short-term rental hosts on Airbnb and other platforms. Our team consists of an ex-Airbnb Staff Data Scientist and Dropbox Sr Software Engineer who are also Superhosts with 9 properties worth $15M making $1.5M/yr.

Midship's AI autonomously performs SOX testing & beyond. Our agents follow your audit plan, perform tests and create fully documented work papers.

Dataleap is a GenAI-powered market research platform for management consulting firms and corporate strategy departments. Think Perplexity for Consultants. We combine the natural language interface from chatGPT with trusted, verifiable market data from best-in-class data providers. We do the heavy lifting of aggregating all data sources into a single interface. We optimize the whole market research workflow from finding the right information, managing the internal knowledge base as well as sharing information with team members. We already work with leading consultancies like BCG and industry giants like Siemens Energy and Uniper.