Play Health

Perimenopause Care Platform

Fall 2025

Active

http://playhealth.com

Perimenopause Care Platform

Play Health is building a perimenopause care platform to provide women and their providers with the tools they need to relieve symptoms fast. It is led by technical, second-time, YC-backed founders Andrea Mazzocchi, PhD and Ian Miller, with an exit and a unicorn between them. Over 30 million women in the U.S. are experiencing perimenopause symptoms, spending an estimated $15B+ annually on symptom management. Despite this most only receive generic solutions and struggle to find effective symptom relief. We're bringing evidence-based perimenopause care to women through partnerships with medical practices and employer and health benefits programs. Our platform integrates personalized symptom, medication, and lifestyle data to generate AI-powered insights and clinical protocols, enabling providers to deliver specialized care. Every clinical interaction enriches our longitudinal dataset allowing us to create better outcomes for patients, deeper insights for providers, and expand into women’s health broadly. This also enables us to partner with pharma and biotech companies developing therapeutics and diagnostics for women's health.

Active Founders

Andrea Mazzocchi

Founder

Co-founder & CEO at Play Health - a perimenopause care platform to improve women's midlife health. Previously, research in tissue engineering, tumor microenvironments, cancer precision medicine. Was also CEO at Known Medicine (S20) which raised ~$8.2M and was ultimately acquired by Pathos AI in spring 2023.

Andrea Mazzocchi

Founder

Ian Miller

Founder & CTO

Co-founder & CTO at Play Health - a perimenopause care platform to improve women's midlife health. Passionate about tech solutions for making people's lives better. Love working with cross-functional teams.

Ian Miller

Founder & CTO

Company Launches

Play Health: Perimenopause Care Platform

See original launch post

TL;DR

Play Health’s Perimenopause Care Platform combines comprehensive symptom + cycle tracking, at-home hormone testing, and AI-driven content to give women actionable, personalized insights to help relieve symptoms and improve quality of life.

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https://www.youtube.com/watch?v=zzmHWl0jhfM

Why It Matters

Perimenopause is when women begin to experience hormonal changes and symptoms of menopause such as brain fog, mood shifts, and hot flashes, while still having their period. It can start in the mid-30s and last 10+ years.

Despite impacting 30M+ women in the U.S. alone, perimenopause remains one of the most overlooked stages in women’s health. The science is complex, the data is sparse, and existing solutions are either too generic or too narrow. Women are left navigating life-altering symptoms with little guidance and few tools.

Perimenopause care today is where fertility care was a decade ago: under-researched, under-funded, and urgently in need of innovation. Play Health is changing that.

Play Health’s Perimenopause Care Platform

Track what matters: cycle, symptoms, lifestyle, supplements, and therapeutics.
Test at home: perimenopause-specific hormone test, designed for real-world use.
Turn data into action: AI-powered personalized insights to relieve symptoms and support long-term health.

By combining personalized care today with a foundational dataset for tomorrow, Play Health is setting a new standard for women’s midlife health.

About Us

Play Health was founded by Andrea Mazzocchi, PhD and Ian Miller, second-time YC founders with a track record of building and scaling impactful companies.

Andrea previously served as CEO of Known Medicine (YC S20), leading its acquisition by Pathos AI in 2023.
Ian co-founded **Gecko Robotics (YC W16)**—now a unicorn—and later led automation and engineering at Known Medicine and Pathos.

Together, they bring deep technical and scientific expertise and a shared mission: to close the massive care gap in women’s health, starting with perimenopause.

Better perimenopause care today. Breakthrough science tomorrow.

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👉 Learn more about Play Health