Skincare Startups funded by Y Combinator (YC) 2026

Soteri Skin is D2C skincare for chronic skin conditions like eczema. We’re the only non-prescription product proven to provide long-lasting relief for the 30 million Americans who suffer from eczema. How it works: Skin surface pH is constantly in flux, and many of your daily activities can throw it out of balance. People with chronic skin conditions such as eczema have a harder time regulating their skin's pH. Soteri's patented pH/LOCK™ locks skin in at a therapeutic pH for 12+ hours, which is shown to help break the cycle of skin sensitivity, whether you have eczema, psoriasis, or just a bad sunburn. Our formulations are aesthetically elegant (non-sticky, sit well under makeup, etc), safe for anyone to use, and don't require a prescription. Most people see skin health improvements within the first few weeks of application, even for tricky, chronic skin conditions like eczema and psoriasis. With Soteri Skin, anyone can enjoy healthy, glowing, pH-enomenal skin!